Western Journal of Medical and Biomedical Sciences

FOREWORD

The volume Six, Issue 17, number One, the first quarter issue of 2025 goes with the title   “Cortical Tubers Without Neurological Symptoms: “An Uncommon Case of Tuberous Sclerosis Complex”. The authors stressed that not all cases of Tuberous Sclerosis Complex (TSC) present with all the classical features as there are also phenotypic non-classical variants of the same disease. That it is a rare genetic neurocutaneous syndrome often characterized by presence of benign nodules in different parts of the body including brain. A thorough clinical and radiological examinations will help diligent physicians to identify non-classical phenotypic variants.

In another study researchers x-rayed Primary Health Care Under One Roof (PHCUOR) In Nigeria in retrospect in order to ascertain the successes and failures attained so far. And they came to the conclusion that the policy which is backed by law has failed to attained the desired impact due to myriad of challenges. Some of which include infrastructural constraints, inadequacy of staff to drive it, and unwillingness of the relevant health personnel to show understanding, work as a team to ensure its success.

Hydroxyurea has been reported to be effective in the management of patients with sickle cell disease and in this vein a team of researchers set out to evaluate the clinical and laboratory outcomes of children with SCA on hydroxyurea therapy. They found that Hydroxyurea therapy significantly reduced the frequency of vaso-occlusive crises (mean reduction from 7.70 to 1.91, p = .000), hospital admissions (mean reduction from 2.60 to 0.84, p = .000), and blood transfusions (mean reduction from 1.51 to 0.40, p = .005) along with significant decrease in hospital stay duration.

Professor Michael Simidele Odimayo

Editor-In-Chief

31^st March, 2025