Perceived Family Support And Patterns Of Medication Adherence Among Adult Patients Attending Antiretroviral Clinic Of A Tertiary Hospital Of Gusau, Northwest Nigeria

Authors

  • Bello MB Federal Medical Centre Gusau Zamfara state Author
  • Shehu A Federal Medical Centre Gusau Author
  • Umar A Federal Medical Centre Gusau Author
  • Daninna ZM Federal Medical Centre Gusau Author
  • Akogwu HS Federal Medical Centre Gusau Author
  • Fatusin BB Federal Medical Centre Abeokuta Author
  • Fatusin AJ University College Hospital, Ibadan image/svg+xml Author
  • Idris RI Federal Medical Centre Gusau, Zamfara state Author
  • Mohammed BA Federal Medical Centre Gusau Zamfara state Author
  • Grema BA Author
  • Muhammad J Federal University Birnin Kebbi image/svg+xml Author

Keywords:

ARV Medication Adherence, HIV Viral Load, Human Immunodeficiency Virus (HIV), Perceived Family Support

Abstract

Human immunodeficiency virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) remain major global health concerns, with about 37.7 million people living with HIV and 28.2 million accessing antiretroviral therapy (ART). Increased ART use has significantly improved treatment outcomes, delayed disease progression, and enhanced survival. However, optimal adherence is essential for viral suppression, and this is influenced by patient-related, socioeconomic, therapy-related, disease-related, and healthcare provider factors. Family support, an important socioeconomic factor, plays a key role in improving adherence among patients with chronic conditions like HIV. This study determined the relationship between perceived family support and medication adherence among adult patients attending the ARV clinic of the Federal Medical Centre, Gusau. A hospital-based cross-sectional study was conducted among 239 patients aged 18 years and above, selected using systematic random sampling over 18 weeks. Data were collected using a self- administered questionnaire covering socio demographic characteristics, the 20-item Perceived Family Support Scale, the 8-item Morisky Medication Adherence Scale, clinical variables, and viral load, with <1,000 copies defined as good suppression. The mean age of participants was 36.64 ± 10.52 years, with females constituting 64.4%. Most respondents (79.9%) had good medication adherence, while 86.6% reported good family support. A strong positive monotonic relationship was found between perceived family support and adherence (Spearman's rho = 0.737, p = 0.01). Lower adherence was associated with low education, being married, poverty, longer duration on ART, and poor family support. The findings indicate that family support significantly improves adherence; therefore, integrating family support assessment into routine care, strengthening family involvement, promoting positive healthcare provider attitudes, improving access to treatment, reducing out-of-pocket costs, and fostering community support to reduce stigma are recommended to enhance adherence and viral suppression.

Author Biographies

  • Bello MB, Federal Medical Centre Gusau Zamfara state

    Department of Family Medicine, Federal Medical Centre,Gusau, Zamfara State, Nigeria.

  • Shehu A, Federal Medical Centre Gusau

    Department of Community medicine, Federal medical Centre, Gusau, Zamfara State, Nigeria.

  • Umar A, Federal Medical Centre Gusau

    Department of Internal Medicine, Federal Medical Centre, Gusau, Zamfara State, Nigeria.

  • Daninna ZM, Federal Medical Centre Gusau

    Department of Family Medicine, Federal Medical Centre, Gusau, Zamfara State, Nigeria.

  • Akogwu HS, Federal Medical Centre Gusau

    Department of Family Medicine, Federal Medical Centre, Gusau, Zamfara State, Nigeria.

  • Fatusin BB, Federal Medical Centre Abeokuta

    Department of Family Medicine, Federal Medical Centre, Abeokuta, Ogun State, Nigeria.

  • Fatusin AJ, University College Hospital, Ibadan

    Department of Family Medicine, University College Hospital, Ibadan, Oyo State, Nigeria.

  • Idris RI, Federal Medical Centre Gusau, Zamfara state

    Department of Family Medicine, Federal Medical Centre, Gusau, Zamfara State, Nigeria.

  • Mohammed BA, Federal Medical Centre Gusau Zamfara state

    Department of Obstetric and Gynaecology, Federal Medical Centre, Gusau, Zamfara State, Nigeria.

  • Grema BA

    Department of Family Medicine, Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria.

  • Muhammad J, Federal University Birnin Kebbi

    Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Federal University Birnin Kebbi, Kebbi State,
    Nigeria.

References

1. UNAIDS: Nigerians living with HIV/AIDS 2019.

https://www.unaids.org/en/resources/presscentre/pr

essreleaseandstatementarchive/2019/march/201903

14_nigeria (accessed 20 March 2022).

2. Kibuuka H, Musingye E, Mwesigwa B,

Semwogerere M, Iroezindu M, Bahemana E, et al.

Predictors of All-Cause Mortality Among People

With Human Immunodeficiency Virus (HIV) in a

Prospective Cohort Study in East Africa and

Nigeria. Clinical Infectious Diseases.

2022;75(4):657-64.

3. Bezabhe WM, Chalmers L, Bereznicki LR, Peterson

GM. Adherence to Antiretroviral Therapy and

Virologic Failure: A Meta-Analysis. Medicine

(Baltimore). 2016;95(15):e3361. doi:

10.1097/MD.0000000000003361 (accessed 20

March 2024).

4. Dorcélus L, Bernard JJ, Georgery C, Vanessa C.

Factors associated with antiretroviral therapy

adherence among people living with HIV in Haiti: a

cross-sectional study. AIDS Res Ther. 2021;

18(1):81. doi:10.1186/s12981-021-00405-4.

(accessed 20 March 2024).

5. Adejumo OA, Malee KM, Ryscavage P, Hunter SJ,

Taiwo BO. Contemporary issues on the

epidemiology and antiretroviral adherence of HIV-

infected adolescents in sub-Saharan Africa: A

narrative review. J Int AIDS Soc. 2015;18(1):20049.

doi:10.7448/IAS.18.1.20049 (accessed 20 March

2024).

6. Ammon N, Mason S, Corkery JM. Factors

impacting antiretroviral therapy adherence among

human immunodeficiency virus–positive

adolescents in sub-Saharan Africa: a systematic

review. Public Health. 2018;157:20-31.

doi:10.1016/j.puhe.2017.12.010. (accessed 20

March 2024).

7. AKharsany AB, Karim QA. HIV infection and

AIDS in sub-Saharan Africa: current status,

challenges and opportunities. The Open AIDS

Journal. 2016; 10:34-48.

8. Abdulsamad H, Oche OM, Raji MO, Mohammed Y.

Prevalence and factors associated with treatment

adherence among patients on highly active

antiretroviral therapy (HAART) in Specialist

Hospital, Sokoto, Nigeria. International Archives of

Medical and Health Research 2019; 1(2):22-28 .

9. Pennap GR, Abdullahi U, Bako IA. Adherence to

highly active antiretroviral therapy and its

challenges in people living with human

immunodeficiency virus (HIV) infection in Keffi,

Nigeria. Journal of AIDS and HIV Research. 2013;

5(2):52-59

10. Anyaike C, Atoyebi OA, Musa OI, Bolarinwa OA,

Durowade KA, Ogundiran A, et al. Adherence to

combined Antiretroviral therapy (cART) among

people living with HIV/AIDS in a Tertiary Hospital

in Ilorin, Nigeria. Pan African Medical Journal.

2019; 32(1):10-17.

11. Damulira C, Mukasa MN, Byansi W, Nabunya P,

Kivumbi A, Namatovu P, et al. Examining the

relationship of social support and family cohesion

on ART adherence among HIV-positive adolescents

in southern Uganda: baseline findings. Vulnerable

Child Youth Stud. 2019;14(2):181-190.

12. Folasire OF, Akinyemi O, Owoaje E. Perceived

social support among HIV positive and HIV

negative people in Ibadan, Nigeria. World Journal of

AIDS. 2014;4(1)15-26.

13. Chinweokwu NU, Onuoha FM, Alabi AN, Nwajei

AI, Owolabi AO, Achigbu KI, et al. The relationship

between perceived family support and adherence to

highly active anti-retroviral therapy among people

living with human immunodeficiency virus in a

tertiary health facility in Nigeria. International

research journal of medicine and medical science

2018; 6(3):79-84

14. Nigeria Bureau of Statistics. Population Statistics.

https://nigerianstat.gov.ng (accessed 10 July 2024).

15. Wikipedia. Federal Medical Centre Gusau. Doi:

Doi:en.wikipedia.org/wiki/Federal_Medical_Centre,

_Gusau, Gusau (accessed 5 September 2025).

16. Yekini IA, Benjamin AA, Kayode FI, Adekola AI.

Medication adherence and social support in people

living with HIV/AIDS (PLWH) in Kogi State,

Nigeria. Journal of AIDS and HIV Research.

2023:15(1):26-40.

17. Desalegn M, Gutama T, Merdassa E, Kejela G, Benti

W. Family and Social Support Among Patients on

Anti-Retroviral Therapy in West Wollega Zone

Public Hospitals, Western Ethiopia: A Facility-

Based Cross-Sectional Study. HIV AIDS

(Auckland). 2022;14:167-179.

18. Inoue Y, Oka S, Yokoyama S, Hasegawa K, Mahlich

J, Schaede U, et al. Medication Adherence of People

Living with HIV in Japan—A Cross-Sectional

Study. InHealthcare 2023:11(4):451.

19. Afolabi BA, Afolabi MO, Afolabi AA, Odewale MA,

Olowookere SA. Roles of family dynamics on

adherence to highly active antiretroviral therapy

among people living with HIV/AIDS at a tertiary

hospital in Osogbo, south-west Nigeria. African

health sciences 2013; 13(4):920-926

20. Jackson IL, Umoh SS, Erah PO. Medication

adherence and health status in HIV positive patients

in Akwa-Ibom State, Nigeria. Tropical Journal of

Pharmaceutical Research. 2020;19(10):451-459.

21. Li XM, Yuan XQ, Rasooly A, Bussell S, Wang JJ,

Zhang WY. An evaluation of the impact of social

support and caregiving on medication adherence of

people living with HIV/AIDS: A nonrandomized

community intervention study. Medicine

(Baltimore). 2018;97(28):e11488. doi:

10.1097/MD.0000000000011488. (accessed 20

March 2024).

22. Knight L, Schatz E. Social Support for Improved

ART Adherence and Retention in Care among Older

People Living with HIV in Urban South Africa: A

Complex Balance between Disclosure and Stigma.

Int J Environ Res Public Health.

2022;19(18):11473. doi: 10.3390/ijerph191811473.

(accessed 20 March 2024).

23. Dalmida SG, McCoy K, Koenig HG, Miller A,

Holstad MM, Thomas T, et al. Examination of the

role of religious and psychosocial factors in HIV

medication adherence rates. Journal of religion and

health. 2017;56(6):2144-2161.

Published

2026-06-30