Managing Acute Coronary Syndrome Amidst Resource Constraints: A Nigerian Case Report

Authors

Keywords:

Acute Coronary Syndrome, Case Report, Nigeria, Resource Constraints

Abstract

Acute coronary syndrome is a cardiovascular disease that is now becoming common in developing countries as a result of the adoption of a westernized lifestyle, high prevalence of hypertension, diabetes mellitus, and obesity. The diagnosis and management are challenging in low-resource countries such as Nigeria due to late presentation, diagnostic challenges, and financial constraints. We present the case of a 63-year-old woman, a known patient with hypertension and diabetes mellitus, who presented with a 5-day history of central crushing chest pain, with associated diaphoresis, vomiting, and preceding easy fatigability. An electrocardiogram (ECG) done at presentation showed widespread myocardial ischaemia, and troponin I was markedly elevated. The coronary computed tomography (CT) coronary angiography done showed near total occlusion of the proximal portion of the left anterior descending artery. A diagnosis of acute coronary syndrome was made. She was counselled for percutaneous coronary intervention (PCI), but she could not afford it. Guideline-directed medical therapy was initiated, and only two serial electrocardiograms were done. Due to financial constraints, there was a delay in getting a CT coronary angiography, inability to do serial ECG and cardiac enzyme monitoring and inability to have PCI, which is the definitive treatment of her condition. She improved with medical therapy only and was subsequently discharged.

Author Biographies

  • Akinfaderin DA, University of Medical Sciences, Ondo

    Department of Internal Medicine, University of Medical Sciences, Ondo,Ondo State, Nigeria.

  • Enikuomehin AC, University of Medical Sciences, Ondo

    Department of Internal Medicine, University of Medical Sciences, Ondo,Ondo State, Nigeria.

  • Junaid OA, University of Medical Sciences, Ondo

    Department of Internal Medicine, University of Medical Sciences, Ondo,Ondo State, Nigeria.

  • Fabusuyi OT, University of Medical Sciences, Ondo

    Department of Internal Medicine, University of Medical Sciences, Ondo,Ondo State, Nigeria.

  • Akinfaderin AW, Ondo State Primary Health Care Development Board

    Nursing Unit, Comprehensive Health center, Arakale, Akure. Ondo State, Nigeria.

References

1. Mohd SE, Muhammad ZN. Cardiovascular risk Score among Adolescents - Review of its methods and outcome. Asian J Med. and Biomedicine.2023; 7(1)39-50

2. Krumholz HM. The Global Burden of Cardiovascular Disease: Not just a mirror, But a Compass. JACC. 2025 Dec; 86(22) 2103-2105.

3. Olvera LE, Ballard BD, Jan A. Cardiovascular Disease.2023 Aug 22. In: StatPearls [internet]. Treasure Island(FL) StatPearls Publishing ;2026 Jan-PMID 30571040

4. N'Guetta R, Yao H, Ekou A, N'Cho-Mottoh MP, Angoran I , Tano M et al. Prevalence and characteristics of acute coronary syndrome in a sub-Saharan Africa population. Ann Cardiol Angeiol (Paris). 2016. Apr; 65(2):59-63.

5. Yao H, Ekou A, Niamkey T, Hounhoui G, Kouame M, Afassinou Y et al. Acute Coronary Syndromes in sub- Saharan Africa. A 10 year systematic Review. J Am Heart Association .2022 Jan 4:11(1): e021107 .

6. Sarr M, Ba DM, Ndiaye MB, Bodian M,Kane A,Diao M, et al. Acute coronary syndrome in young sub-Saharan Africans: a prospective study of 21 cases. BMC Cardiovasc Disord. 2013 Dec 14;13: 118.

7. Shahjehan RD, Sharma S,Dababneh E, Bhutta BS, . Coronary Artery Disease.In: StatPearls[internet].Treasure Island(FL) StatPearls. 2024 Oct 9, Publishing: 2026 Jan.PMID 33231974.

8. Ndiaye PG, Ngaide AA, Souleiman A, Fall PM, Mingou JS, Diop CM. et al. Profile and management of non-ST-segment elevation acute coronary syndromes hospitalized in Dakar. Ann Cardiol Angeiol (Paris). 2026 Feb; 75(1):e101983.

9. Aderinto N, Olatunji D. Assessing the condition of percutaneous coronary intervention services in Africa: Challenges and prospects for advancement. Ann Med Surg (Lond).2023 May 24; 85(6):2814-2820.

10. Singh A, Museedi AS, Grossman SA. Acute Coronary Syndrome.2023 Jul 10.In:StatPearls[Internet].Treasure Island (FL): StatPearls Publishing; 2026 Jan – PMID 29083796. URL:https://pubmed.ncbi.nlm.nih.gov/29083796/

11. Xia K, Wang LF, Yang XC, Jiang HY, Zhang LJ, Yao DK et al. Comparing the effects of depression , anxiety and comorbidity on quality of life, adverse outcomes and medical expenditure in Chinese patients with Acute coronary syndrome. Chin Med J(Engl). 2019 May 5; 132(9):1045-1052

12. Shavadia J, Yonga G, Otieno H. A prospective review of acute coronary syndromes in urban hospital in sub-Saharan Africa. Cardiovasc J Afr. 2012 Jul ;23(6):318-21

13. Ojo A, Atoe-Imagbe OM, Agu-Jefferson I, Ogbemudia E, Ogbomo A, Josephs V. et al. Epidemiology and short -Term Outcomes of Acute coronary Syndrome in a Nigerian Tertiary Hospital. A prospective Cohort Study. Cureus 2026 Feb 20;18(2):e104005

14. Achar SA, Kundu S, Norcross WA. Diagnosis of acute coronary syndrome. Am Fam Physicians. 2005 Jul1;72(1):119-26

15. Ameen MM, Malavan MA. Prevalence and predictors of Occlusive Myocardial Infarction in Patients presenting with Non-ST-elevation Acute coronary syndrome in Duhok ;A cross sectional study. Cureus .2024 Jul 24;16(7)

16. Mboup MC, Mingou J, Ba DM, Dia K, Fall PD; Characteristics of acute coronary syndrome in sub-Saharan African women. Ann Cardiol Angeiol (Paris) 2019,Apr; 68(2):115-119.

Published

2026-05-28