Knowledge, Perception and Uptake of Human Papilloma Virus Vaccine Among Secondary School Adolescents in Makurdi, Benue State

Authors

  • Ukpabi DE BENUE STATE UNIVERSITY Author
  • Ocholongwa EC Benue State University image/svg+xml Author
  • avershima IC Federal medical centre jalingo Author
  • Adajime PT Benue State University image/svg+xml Author
  • Michael AM Benue State University image/svg+xml Author
  • Rimamnunra GN Benue State University image/svg+xml Author
  • Odunze P Gombe state ministry of health Author

Keywords:

Adolescence, Cervix, Cervical cancer, Human papillomavirus, Vaccine

Abstract

Cervical cancer is the second most common malignancy among Nigerian women and is regarded as a major public health concern worldwide. Human papillomavirus (HPV) infection is the cause of cancer in women by generating malignant changes in the cervix. The HPV vaccine is already available to prevent it, but its use is limited. The study aimed to determine the knowledge, perception, and uptake of the human papillomavirus vaccine among adolescent females in selected secondary schools in Makurdi, Benue State. The study was a cross-sectional study done in secondary schools in Makurdi, Benue State, North Central Nigeria. A multistage sampling technique was used to select 363 secondary school girls who participated in the study. Data was collected using interviewer-administered questionnaires, was analyzed using Statistical Package for Social Sciences (SPSS) version 25, and presented in tables. The study revealed that the majority of the girls were between 13 and 16 years. A vast majority (62.3%) had poor knowledge of HPV and its vaccine, more than half also had poor perception of the vaccine (51.5%), and the uptake of the vaccine was significantly low (5.5%). The knowledge, perception, and uptake of the HPV vaccine among secondary school girls is low. The government should make efforts to improve the awareness and uptake of the vaccine to ensure Nigeria reduces the incidence and prevalence of cervical cancer.

Author Biographies

  • Ukpabi DE, BENUE STATE UNIVERSITY

    Department of Epidemiology and Community Health, Rev Fr Moses Adasu University, Makurdi, Benue State Nigeria

  • Ocholongwa EC, Benue State University

    Department of Epidemiology and Community Health, Benue State University Teaching Hospital, Makurdi, Benue State Nigeria .

  • avershima IC, Federal medical centre jalingo

    Federal Medical Centre, Jalingo, Taraba State Nigeria.

  • Adajime PT, Benue State University

    Department of Epidemiology and Community Health, Rev Fr Moses Adasu University, Makurdi, Benue State Nigeria.

  • Michael AM, Benue State University

    Department of Epidemiology and Community Health, Benue State University Teaching Hospital, Makurdi, Benue State Nigeria .

  • Rimamnunra GN, Benue State University

    Department of Epidemiology and Community Health, Rev Fr Moses Adasu University, Makurdi, Benue State Nigeria.

  • Odunze P, Gombe state ministry of health

    Gombe State Ministry of Health, Gombe, Gombe State, Nigeria

References

1. John-Akinola YO, Olorunyomi FO, Mojisola MO. Effect of an educational intervention on awareness, knowledge, perception and intention to uptake HPV vaccination among female in-school adolescents in Ibadan, Oyo State, Nigeria. European Journal of Public Health Studies. 2024;7(2):71-84.

2. Agida TE, Akaba GO, Isah AY, Ekele B. Knowledge and perception of human papilloma virus vaccine among the antenatal women in a Nigerian tertiary hospital. Nigerian Medical Journal. 2015;56(1):23-27

3. Stefan DC, Dangou JM, Barango P, Mahamadou ID, Kapambwe S. Targeting elimination of cervical cancer by 2030: a baseline assessment in six African countries-part II. Ecancermedicalscience. 2022 Oct 7;16:1454. doi: 10.3332/ecancer.2022.1454. PMID: 36405933; PMCID: PMC9666272.

4. Beatrice O, Abiola OA, Chiemerigo AO. Knowledge, attitudes and perceptions of Nigerian parents towards human papilloma virus (HPV) vaccines. European Journal of Midwifery. 2020;4:2

5. Folusho B, Olayemi O. “She must have been sleeping around”…: Contextual interpretations of cervical cancer and views regarding HPV vaccination for adolescents in selected communities in Ibadan, Nigeria. PLoS ONE. 2018;13(9):203950

6. Ndikom CM, Oboh PI. Perception, acceptance and uptake of human papillomavirus vaccine among female adolescents in selected secondary schools in Ibadan, Nigeria. African Journal of Biomedical Research. 2017;20(3)

7. WHO. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva. 2020. Available at https://iris.who.int/server/api/core/bitstreams/4e245e89-ddcc-488f-97c7-9de5e08524ef/content

8. Christian CM, Rose IA, Kofoworola AO. Human papillomavirus (HPV) infection and vaccines: Knowledge, attitude and perception among female students at the University of Lagos, Lagos, Nigeria. Journal of Epidemiology and Global Health. 2012;2:199-206

9. Maier C, Maier T, Neggu CE, Vladareanu R. Romanian adolescents' knowledge and attitudes towards human papilloma virus infection and prophylactic vaccination. European journal of Obstetrics & Gynecology and Reproductive Biology. 2015;195:77

10. Michael CE, Biodun NO. Human papilloma virus vaccine: Determinants of acceptability by mothers for adolescents in Nigeria. African Journal of Reproductive Health. 2014;18(3):154

11. Mwansa KL, Carla JC, Mulindi M, Moses M, Simone F, Mary K. Adolescent girls' knowledge and perceptions regarding the human papillomavirus vaccine. Frontiers in Health Services. 2023;3:1208458

12. Tope O, Elijah AO, Marcellina OC, Surajudeen AO, Waheed AE, Joke OO et al. HPV vaccine knowledge, attitude, and programme satisfaction among parents and caregivers of vaccine recipients in Ogun state Nigeria. National Library of Medicine. 2024;21(1):179

13. Rabiu KA, Alausa TG, Akinlusi FM, Davies NO, Shittu KA, et al. Parental acceptance of human papillomavirus vaccination for adolescent girls in Lagos, Nigeria. Journal of Family Medicine and Primary Care. 2020;9(6):2950-2957

14. Balogun F, Omotade O. “She must have been sleeping around”…: Contextual interpretations of cervical cancer and views regarding HPV vaccination for adolescents in selected communities in Ibadan, Nigeria. PLoS ONE 2018; 13(9): e0203950. https://doi.org/10.1371/journal.pone.0203950

15. United Nations World population prospects. Available from https://www.macrotrends.net/cities/23539/makurdi/population. Retrieved 2025-02-04.

16. Funmilayo FA, Balogun RB, Adekemi OS, Adebukola AA. Cervical cancer and human papilloma virus knowledge and acceptance of vaccination among medical students in Southwest Nigeria. African Journal of Reproductive Health 2015;19(1):140-148

17. Ragin CC, Edwards RP, Jones J et al. Knowledge about human papillomavirus and the HPV vaccine – a survey of the general population. Infect Agents Cancer 4. 2009;4(S10):1186/1750-9378

18. Jacqueline DH, Natalia LK, Juliana C, Marina B, Glaucia H, Eliana MW. Human papillomavirus knowledge, beliefs, and behaviours: A questionnaire adaptation. European journal of Obstetrics & Gynaecology and Reproductive Biology. 2018; 230:103-108

19. Rosella S, Silvia M, Brigid U, Leda S, Guglielmo G, Elisabetta DV et al. Validation of a questionnaire for young women to assess knowledge, attitudes and behaviours towards cervical screening and vaccination against HPV in Italy. Epidemiology Biostatistics and Public Health. 2014;11(2):8913

20. Rabiu, Kabiru A, Alausa, Taiwo G, Akinlusi, Fatimat M, Davies NO, Shittu KA, Akinola OI. Parental acceptance of human papillomavirus vaccination for adolescent girls in Lagos, Nigeria. Journal of Family Medicine and Primary Care. Journal of Family Med and Primary Care. 2020 Jun 30;9(6):2950-2957. Available at doi: 10.4103/jfmpc.jfmpc_102_20. eCollection 2020 Jun.

21. Anyaka CU, Alero B, Olukoya B, Envuladu EA, Musa J, Sagay, Atiene S. Parental knowledge of HPV infection, cervical cancer and the acceptance of HPV vaccination for their children in Jos, Nigeria. Journal of West African College of Surgeons [Internet]. 2024;14(2). Available from:http://journals.lww.com./jwas/fulltext/2024/1420/parental_knowledge of hpv_infaction, cervical.4.asp

22. Sohaila C, Amit A, Patrick M, Anupama J, Karima C, Reem AJ et al. HPV infection and vaccination: a cross sectional study of knowledge, perception, and attitude to vaccine uptake among university students in Qatar. BMC Public Health. 2024;24:231641.

23. Cinar, İO., OzkanS., Aslan, GK., & Alatas E. Knowledge and Behavior of University Students toward Human Papillomavirus and Vaccination. Asia-Pacific Journal of Oncology Nursing 2019; 6(3), 300–307.

24. Adeniyi FI, John-Akinola YO, Oluwasanu MM. Intention and concerns about HPV vaccination among in-school adolescents in Ibadan, Oyo State, Nigeria. Niger Med J. 2023 Jul 2;64(3):352-364

25. Akinleye HW, Kanma-Okafor OJ, Okafor IP, Odeyemi KA. Parental willingness to vaccinate adolescent daughters against human papilloma virus for cervical cancer prevention in Western Nigeria. Pan Afr Med J. 2020 Jun 19;36:112.

26. Josephat JN, Halama RB, Makiriye HF, Farah A, Haule I, Kirumbuyo M, Amour C, Msuya SE. Factors Associated with the Uptake of Human Papilloma Virus Vaccine Among Adolescent Girls Aged 14 Old in Hai District of Kilimanjaro Region in Northern Tanzania. East Afr Health Res J. 2024;8(2):264-270.

27. Mihretie, Gedefaye Nibret, Liyeh, Tewachew Muche, Ayele AD, Belay HG, Yimer, Tigist Seid, Miskr, Agernesh Dereje, et al. Female adolescents' knowledge and acceptability of human papillomavirus vaccine in Debre Tabor Town, Ethiopia: a cross-sectional study. BMJ Open [Internet]. 2023 Mar 1;13(3):e061813. Available from: http://bmjopen.bmj.com/content/13/3/e061813.abstract.

Published

2026-03-31